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Racemic mixture vs meso compound

Short answer

A racemic mixture is an equimolar mixture of two enantiomers, optically inactive due to external cancellation, and can be separated. A meso compound is a single achiral molecule with chiral centers but an internal plane of symmetry, permanently inactive and cannot be resolved.

Differentiate between racemic mixture and meso compound.

BasisRacemic mixtureMeso compound
NatureEquimolar mixture of two enantiomers (d + l)A single pure compound
Chiral centresEach molecule is chiralHas chiral centres but is achiral overall
Cause of inactivityExternal compensationInternal compensation (plane of symmetry)
ResolutionCan be separated into d and l formsCannot be resolved
Example(±)-lactic acid, (±)-tartaric acidmeso-tartaric acid

✓ Answer checked by Claude Opus 5.5 (high effort)

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